Endocrine Abstracts

Case history: A 50 year old female presented with diarrhoea, facial rash and hyponatraemia. In addition, she described a 3 week history of headaches, malaise, intermittent joint pain and swelling. On examination, the patient was noted to have a malar rash and over the subsequent 2–3 days began to develop necrotic patches on both ears. She had no evidence of cutaneous pigmentation. She took no regular medication, other than dabigatran. Past medical history of note included...

Background: Adrenocortical carcinoma (ACC) is a rare malignant tumour of the adrenal cortex with an incidence of 0.7-2.0 per million per year. The majority are steroid-producing with non-ACTH dependent hypercortisolism the most frequent biochemical abnormality. Around 10-15% of cases are picked up incidentally on abdominal imaging. Management of ACC during the covid-19 pandemic poses specific challenges. We present the case of a 69-year-old man who was found to have a massive ...

Section 1: Case history : The case concerns a 53-year-old gentleman who developed calciphylaxis following a bioprosthetic aortic valve replacement. His past medical history included Multiple Endocrine Neoplasia Type 1 (MEN-1) for which he had previously undergone total parathyroidectomy with failed graft auto-transplantation. The resulting hypoparathyroidism was managed with alfacalcidol and calcium supplements. Post cardiac valve replacement he developed acute renal injury an...

Introduction: Immune adverse related events are commonly recognized complications of immune check point inhibitors. Here we identify multiple endocrinopathies occurring concurrently in the same patient. In addition to highlighting the common immune adverse effects seen in other cases.Case 1: 33F Refractory Hodgkins Lymphoma tried on several therapies. She was started on Nivolumab (PD-1) with remarkable response. She developed symptoms of Amenorrhea, gala...

Introduction: Immune adverse related events are commonly recognized complications of immune check point inhibitors. Here we identify multiple endocrinopathies occurring concurrently in the same patient. In addition to highlighting the common immune adverse effects seen in other cases.Case 1: 33F Refractory Hodgkins Lymphoma tried on several therapies. She was started on Nivolumab (PD-1) with remarkable response. She developed symptoms of Amenorrhea, gala...